Scales used in multiple indications
Chronic diseases have an impact on the everyday life of the sufferers. So whatever the underlying cause of their chronic illness, the objective of a new treatment is always to improve life. Alleviating the symptoms is one thing, but ameliorating global health and quality of life is even better.
At Healint, this is definitely the objective we try to reach. That is why we are here to help new treatments and procedures demonstrate their efficacy as fast and qualitatively as possible. We are proud to say that we are able to dramatically reduce significantly the time to conduct a study. No false promise. We have a track record that shows we could almost divide by two the time between FPI (first patient included) and DBL (database lock).
Below are a few scales that we run for any relevant indication. Our HeRO™ tool and our methodology allow us to collect the best quality data. Most of these scales are Patient Reported Outcomes for which trial participants can use their own device. It makes their life easier and dramatically increase compliance and reduces drop out.
EQ-5D-5L
(PRO)
This very popular scale is used in a large number of indications and all types of studies (observational, population health, clinical trial…) It can be used longitudinally or to compare groups. It assesses 5 dimensions of quality of life: Mobility, self-care, usual activities, pain/discomfort, and anxiety/depression + an estimate of health level on a scale from 0 to 100. The evaluation is about the day when the questionnaire is completed. The results can be presented in various ways: as a description of health profile, as a measure of overall self-rated health status, or from an index value.
SF-36
(PRO)
Short Form - 36 questions, is a self-reported survey that assesses the patient’s quality of life. It is a set of thirty-six generic questions that cover 8 dimensions: vitality, physical functioning, bodily pain, general health perceptions, physical role functioning, emotional role functioning, social role functioning, and mental health. This scale is extremely widely used in clinical trials, although rarely as the primary endpoint.
PHQ-9
(PRO)
The Patient-Health Questionnaire is the depression module of the self-administered version of PRIME-MD diagnostic instrument for common mental disorders. It is a tool used to monitor the severity of depression and response to treatment. It is not a screening tool, but the 2 question version, PHQ-2 can be used for this purpose.
C-SSRS
(ClinRO)
The Columbia Suicide Severity Rating Scale must be conducted by a trained professional. The type of question asked in this questionnaire can reveal important information about the patient, that may require immediate help. The suicidal risk is assessed by the individual administering the scale. What our HeRO™ does is assist the professional in the conduction of the interview.
Other PROs
(PRO)
Patient Global Impression of change (PGIC), Sleep disturbance Numerical Rating Scale (Sleep NRS), Insomnia Severity Index (ISI), Patient Global Assessment (PGA), global treatment satisfaction etc… We collect any PRO required by the protocol of your study.